Friday, 12 December 2014

Antidepressants Pills Names

 Antidepressants Pills Names

Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraines, attention-deficit hyperactivity disorder (ADHD), substance abuse and sleep disorders. They can be used alone or in combination with other medications.
The most important classes of antidepressants are the selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs). Other drugs used or proposed for the treatment of depression include buprenorphine, low-dose antipsychotics, and St John's wort

List of antidepressants

This is a complete list of clinically-approved antidepressants, as well as drugs used to augment antidepressants, by pharmacological and/or structural classification. Chemical/generic names are listed first with brand names in parentheses.

Selective serotonin reuptake inhibitors (SSRIs)

Zimelidine (Normud, Zelmid) and indalpine (Upstene) were also formerly used as antidepressants, but were withdrawn from the market.

Serotonin-norepinephrine reuptake inhibitors (SNRIs)

Serotonin modulators and stimulators (SMSs)

These drugs act as serotonin reuptake inhibitors and agonize/antagonize various serotonin receptors.

Serotonin antagonists and reuptake inhibitors (SARIs)

These drugs act as antagonists of various serotonin receptors and as weak serotonin reuptake inhibitors.
Nefazodone (Nefadar, Serzone) was also formerly used as an antidepressant, but was withdrawn from the market.

Norepinephrine reuptake inhibitors (NRIs)

Atomoxetine (Strattera) is also sometimes used as an antidepressant, but is not specifically approved for this purpose.

Tricyclic antidepressants (TCAs)

Butriptyline (Evadyne), demexiptiline (Deparon, Tinoran), imipraminoxide (Imiprex, Elepsin), iprindole (Prondol, Galatur, Tetran), metapramine (Timaxel), propizepine (Depressin, Vagran), and quinupramine (Kinupril, Kevopril) were also formerly markted, but have since been discontinued.
The following are also TCAs, but are atypical pharmacologically:
Amineptine (Survector, Maneon) is another atypical TCA, acting as a norepinephrine-dopamine reuptake inhibitor (NDRI), but was withdrawn from the market.
Tiazesim (Altinil) is not a TCA, but is a bicyclic antidepressant that is closely related structurally and pharmacologically. Similarly to many TCAs, it is no longer marketed.

Tetracyclic antidepressants (TeCAs)

Mianserin, mirtazapine, and setiptiline are also sometimes described as noradrenergic and specific serotonergic antidepressants (NaSSAs).

Monoamine oxidase inhibitors (MAOIs)

Irreversible

Non-selective

Many others, including benmoxin (Neuralex), iproclozide (Sursum), iproniazid (Marsilid), mebanazine (Actomol), nialamide (Niamid), octamoxin (Ximaol), pheniprazine (Catron), phenoxypropazine (Drazine), pivhydrazine (Tersavid), and safrazine (Safra) were used as antidepressants in the past, but have since been discontinued.

Selective for MAO-B

Reversible

Non-selective

Caroxazone (Surodil, Timostenil) was formerly used as an antidepressant, but has been discontinued.

Selective for MAO-A

These drugs are sometimes described as reversible inhibitors of MAO-A (RIMAs).
Eprobemide (Befol) and minaprine (Brantur, Cantor) were also formerly used as antidepressants, but have been discontinued.

Others

Marketed

Discontinued/withdrawn from the market

Over-the-counter

The following antidepressants are available both with a prescription and over-the-counter:

Adjunctive treatments

This category includes drugs that are generally not considered to be significantly effective as treatments for depression alone, but have demonstrated effectiveness in the augmentation of other antidepressants.

Atypical antipsychotics

Others

Combination products

Currently in clinical trials (investigational)

It is thought antidepressants work by increasing levels of a group of chemicals in the brain called neurotransmitters. Certain neurotransmitters, such as serotonin and noradrenaline, can improve mood and emotion, although this process is not fully understood.
Antidepressants Pills Names
This information about antidepressants, take in the sites:

http://www.nhs.uk/conditions/Antidepressant-drugs/Pages/Introduction.aspx
http://en.wikipedia.org/wiki/List_of_antidepressants
Before treatment antidepreesantami, you should consult a physician.

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posted by Unknown @ 23:47   0 Comments

Wednesday, 10 December 2014

Generic Mirtazapine Remeron Pill

Suicidality and Antidepressant Drugs

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. 
Anyone considering the use of REMERON® (mirtazapine) Tablets or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24 - there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. 
Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. REMERON is not approved for use in pediatric patients.


Mirtazapine (brand names: Avanza, Axit, Mirtaz, Mirtazon, Remeron, Zispin) is a noradrenergic and specific serotonergic antidepressant (NaSSA) that was introduced by Organon International in the United States in 1996 and is used primarily in the treatment of depression. It is also commonly used as an anxiolytic, hypnotic, antiemetic and appetite stimulant. In terms of structure, mirtazapine can also be classified as a tetracyclic antidepressant (TeCA) and is the 6-aza analogue of mianserin. It is also racemic and comes as a combination of both R and S-stereoisomers.
Its patent expired in 2004 and hence generic versions are now availableREMERON® (mirtazapine) Tablets are an orally administered drug. Mirtazapine has a tetra-cyclic chemical structure and belongs to the piperazino-azepine group of compounds. It is designated 1,2,3,4,10,14b-hexahydro-2-methylpyrazino [2,1-a] pyrido [2,3-c] benzazepine and has the empirical formula of C17H19N3. Its molecular weight is 265.36. The structural formula is the following and it is the racemic mixture: http://en.wikipedia.org/wiki/Mirtazapine

REMERON® (mirtazapine) Structural Formula Illustration
Mirtazapine is a white to creamy white crystalline powder which is slightly soluble in water.
REMERON is supplied for oral administration as scored film-coated tablets containing 15 or 30 mg of mirtazapine, and unscored film-coated tablets containing 45 mg of mirtazapine. Each tablet also contains corn starch, hydroxypropyl cellulose, magnesium stearate, colloidal silicon dioxide, lactose, and other inactive ingredients.
http://www.rxlist.com/remeron-drug.htm

What are the precautions when taking mirtazapine Remeron!

Before taking this medication, tell your doctor or pharmacist if you are allergic to it, or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: history or family history of psychiatric disorders (e.g., bipolar/manic-depressive disorder), history or family history of suicide attempts, liver disease, kidney disease, seizures, high blood cholesterol or triglyceride levels, heart disease (e.g., recent heart attack, angina), stroke, severe loss of body fluids (dehydration), low blood pressure.
Systematic (IUPAC) name
(±)-2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
Clinical data
Trade names Remeron, Avanza, Axit, Mirtazon, Zispin
AHFS/Drugs.com monograph
MedlinePlus a697009
Licence data US FDA:link
Pregnancy cat.
Legal status
Routes Oral
Pharmacokinetic data
Bioavailability 50%
Protein binding 85%
Metabolism Liver (CYP1A2, CYP2D6, and CYP3A4)
Half-life 20–40 hours
Excretion Urine (75%)
Faeces (15%)
Identifiers
CAS number 61337-67-5 Yes
ATC code N06AX11
PubChem CID 4205
DrugBank DB00370
ChemSpider 4060 Yes
UNII A051Q2099Q 
KEGG D00563 Yes
ChEBI CHEBI:6950 
ChEMBL CHEMBL654 Yes
Synonyms 6-Azamianserin, Org 3770
Chemical data
Formula C17H19N3 
Mol. mass 265.35 g/mol
Physical data
Density 1.22 g/cm³
Melt. point 114–116 °C (237–241 °F)
Boiling point 432 °C (810 °F)
Solubility in water Soluble in methanol and chloroform mg/mL (20 °C)

What are the possible side effects of mirtazapine Remeron!

Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

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posted by Unknown @ 06:32   0 Comments